Forensic Toxicology

This session explores forensic toxicology, emphasizing the detection, analysis, and interpretation of drugs, poisons, and other toxic agents in biological specimens for legal, clinical, and investigative purposes. The session will focus on the biological mechanisms of toxicity, including how drugs and chemicals are metabolized, distributed, and eliminated, and how these processes influence detection, interpretation, and determination of cause of death or impairment. Participants will learn about analytical techniques used in forensic investigations, including chromatography, mass spectrometry, immunoassays, and emerging high-throughput methods, and how these tools provide quantitative and qualitative data critical for legal and clinical decision-making. Case studies will illustrate practical challenges such as distinguishing therapeutic use from overdose, identifying delayed or cumulative toxicity, and interpreting postmortem redistribution effects. The session will also address the biological variability in drug metabolism, genetic factors, and interactions that can complicate forensic analysis. Legal, ethical, and regulatory considerations, including chain of custody, documentation, and admissibility of evidence, will be highlighted to ensure forensic accuracy and integrity. Additionally, emerging trends such as metabolomics, digital toxicology databases, and rapid point-of-care detection methods will be discussed for their potential to enhance forensic investigations. By combining biological, analytical, and legal perspectives, this session aims to equip participants with the knowledge and skills necessary to accurately detect and interpret toxic exposures, support justice, and contribute to public safety.

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