Clinical Pharmacology and Toxicology

Bio-equivalence is defined as the observation and finding similarities of one or more drugs. Formulations involve the same active substance or element are called bio-equivalence. If their rate of absorption and formulations are identical, they are pronounced to be bioequivalence drugs. The United States food and Drug Administration (FDA) has explained bio-equivalence as "the absence of a significant difference in the rate and range to which the active ingredient or active subdivision in pharmaceutical equivalents or pharmaceutical substitute becomes available at the site of drug action when administered at the same molar dose below similar conditions in an appropriately designed study.

• Rate Of immersion
• Expression of Medicines